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IRGM promotes melanoma cell survival through autophagy and is a promising prognostic biomarker for clinical application: Molecular Therapy - Oncolytics
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Autoimmunity gene IRGM suppresses cGAS‐STING and RIG‐I‐MAVS signaling to control interferon response | EMBO reports
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Autoimmunity Risk Gene IRGM is a Master Negative Regulator of Interferon Response by Controlling the Activation of cGAS-STING and RIG-I-MAVS Signaling Pathways | bioRxiv
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Variants in the autophagy-related gene IRGM confer susceptibility to non-alcoholic fatty liver disease by modulating lipophagy - ScienceDirect
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Autoimmunity gene IRGM suppresses cGAS‐STING and RIG‐I‐MAVS signaling to control interferon response | EMBO reports
![Inhibition of IRGM establishes a robust antiviral immune state to restrict pathogenic viruses | EMBO reports Inhibition of IRGM establishes a robust antiviral immune state to restrict pathogenic viruses | EMBO reports](https://www.embopress.org/cms/asset/b651cbe6-2752-404d-ac57-5b12fb40c30f/embr202152948-abs-0001-m.jpg)
Inhibition of IRGM establishes a robust antiviral immune state to restrict pathogenic viruses | EMBO reports
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Immunity-related GTPase IRGM at the intersection of autophagy, inflammation, and tumorigenesis | Inflammation Research
![Role of Mutations in NOD2/CARD15, ATG16L1, and IRGM in the Pathogenesis of Crohn's Disease | Semantic Scholar Role of Mutations in NOD2/CARD15, ATG16L1, and IRGM in the Pathogenesis of Crohn's Disease | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/aef67c5a97a382fca166e89668f42e519a6679fe/3-Figure2-1.png)
Role of Mutations in NOD2/CARD15, ATG16L1, and IRGM in the Pathogenesis of Crohn's Disease | Semantic Scholar
![The Crohn's Disease Risk Factor IRGM Limits NLRP3 Inflammasome Activation by Impeding Its Assembly and by Mediating Its Selective Autophagy - ScienceDirect The Crohn's Disease Risk Factor IRGM Limits NLRP3 Inflammasome Activation by Impeding Its Assembly and by Mediating Its Selective Autophagy - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S1097276518309882-fx1.jpg)
The Crohn's Disease Risk Factor IRGM Limits NLRP3 Inflammasome Activation by Impeding Its Assembly and by Mediating Its Selective Autophagy - ScienceDirect
![The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage | Genome Biology | Full Text The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage | Genome Biology | Full Text](https://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fgb-2005-6-11-r92/MediaObjects/13059_2005_Article_1127_Fig8_HTML.jpg)
The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage | Genome Biology | Full Text
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Role of Mutations in NOD2/CARD15, ATG16L1, and IRGM in the Pathogenesis of Crohn's Disease | Semantic Scholar
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